The configuration, function, working principle and design method of a wireless remote measurement system of drill hydrology based on GPRS were introduced in this paper. The system can measure water level,water temperature and turbidity of drillhole by intelligent sensors, then use GPRS module to transmit the measured data to monitoring computer by wireless mode, so as to realize processing of the data and forecasting and predicting of water disaster. The system has many advantages such as low cost, flexible configuration, reliable transmission and real-time on-line.