Abstract: In view of problems of low data transmission efficiency and response speed and bad user experience between client and server in traditional development of enterprise Web application, the paper proposed a development scheme of enterprise Web application based on Struts2+jQuery Ajax, and the scheme was applied to development of small and medium-scaled coal enterprise customer relationship management system. It introduced whole framework and implementation of main function modules of the system in details. The actual application showed that the scheme of Struts2+jQuery Ajax can effectively improve development efficiency and maintainability and scalability of customer relationship management system, and greatly improves response speed of Web application program and effect of user experience.