Abstract: The existing research only analyzes the rock burst appearance characteristics under specific conditions, lacks research on the rock burst appearance induced by coal pillar under the condition of thick and hard roof. In order to solve this problem, taking I010203 working face of a mine in Xinjiang as the research object, the paper analyzes the characteristics and causes of working face rock burst under the condition of thick and hard roof multi-seam mining by means of field monitoring and numerical simulation. By analyzing the spatial distribution law of microseismic and large energy events monitored on site, the distribution characteristics of support pressure, and the distribution characteristics of surrounding rock stress during the mining of the working face simulated by numerical simulation, this paper obtained the following results. The stress concentration and the microseismic event density in the transport roadway area of the working face are higher than those in the return air roadway area. And the stress concentration and microseismic event density in the roof and coal seam area are higher than those in the floor area. Based on the above results, the causes of coal pillar rock burst appearance in the mining process of I010203 working face are analyzed by using rock burst caused by dynamic and static combined load theory. ① It is easy to produce lateral overhanging roof above the coal pillar in the transport roadway section. The sudden breaking of the long overhanging roof generates a large amount of dynamic loads. At the same time, a large amount of static loads accumulate on the coal pillars and the roof during the mining process. When the superposition of the two exceeds the critical load, it may cause the rock burst appearance of the working face or a large energy event. The mining process of the I010203 working face mainly includes the main controlling factors such as coal pillar concentrated stress, overlying roof and surrounding rock supporting stress. Therefore, it is easy to produce coal pillar type and thick hard roof caving type rock burst appearance. ② When the mining position of the working face gradually approaches the boundary of the ‘knife shape’ goaf, the boundary stress is transferred downward to the I010203 working face, which leads to the further increase of the rock burst risk of the I010203 working face.