Abstract: In view of problem that current researches mostly focused on mechanical properties of similar material of coal-rock, but not change law of acoustic wave velocity, similar material of coal-rock was made by use of raw materials of coal slime, sand, cement and water, and influence of different ratio of the similar materials on acoustic wave velocity was investigated by adopting range analysis method and orthogonal experiment. The experimental results show that acoustic wave velocity of the similar material is similar to coal-rock and can be adjusted in a large range, which meets requirements of acoustic wave velocity of coal-rock to similar material; acoustic wave velocity of the similar material is obviously influenced by cement content, next by coal slime content and little by sand content, and acoustic wave velocity is postively related to cement content and coal slime content; there is a good linear positive correlation between primary wave velocity and shear wave velocity of the similar material. Empirical equations for calculating ratio of the similar material were obtained by multiple linear regression of the experiment data, which were for making similar material of coal-rock meeting requirement of acoustic wave velocity.