Abstract: The paper analyzed present situation and existing problems of occupational health management of coal enterprises, put forward design scheme of occupational health management system of coal enterprises based on informatization technology. It also introduced design and implementation of system's function module in detail. The system adopts B/S structure, and uses computer platform and mobile platform to brow related information and process business. The system can effectively solve problems of low work efficiency and statistics data deviation of occupational health management of enterprise, and provide an effective mean for occupational health management.