Abstract: The paper proposed to use novel global harmony search algorithm to solve economical dispatch problem, and designed a novel method of treating system constraints. It introduced mathematical model of the economic dispatch problem, implementation procedure and application method of the novel global harmony search algorithm. The experimental results show that the optimal value obtained by novel global harmony search algorithm is much better than the value obtained by evolutionary algorithm and particle swarm algorithm. The novel global harmony search algorithm provides a new solution for solving economical dispatch problems.