Abstract: In order to improve performance of vehicle engine cooling system, the paper proposed a design scheme of intelligent control system for vehicle cooling fan combined with new vehicle network bus technology of FlexRay. The system uses multi-parameter composite linear control signal, namely collects temperature data of the cooling system and working state parameters of the engine, and sends them to MCU for integrated treatment, then MCU outputs PWM control signal. It achieves real-time and efficient control for the cooling fan. The test results show that the system is able to achieve data reading and writing and transmission among multi-node with high real-time performance, reliability and accuracy.