Abstract: The paper introduced an implement scheme of 3D on-line analysis system of mine ventilation. The system uses module of enterprise manager of basic information platform of digital mine based on 3DGIS to arrange, process and store underground data, and creates ventilation network topology automatically according to data of roadway network, ventilation facilities and ventilation equipments of the module. The system can monitor running status of ventilation system on the basis of real-time wind speed data monitored by mine safety monitoring and control system and calculation algorithm of ventilation network, analyze causes of abnormal ventilation, and display analysis results in the form of 3D form by use of module of enterprise application platform of basic information platform of digital mine based on 3DGIS. The application of the system in Sitai Mine achieved a good effect.