Abstract: A design scheme of mine-used multi-protocol translation gateway based on Intel XScale 32-bit microprocessor PXA270 was put forward, design of hardware structure and driving programs of character and network devices were described, and translation principle among multi-protocol was introduced in details. The gateway solves problems of multi-network interconnection and wire network monitoring blind spots in coal mine underground by integration of kinds of networks of CAN, Ethernet, wireless and so on.