Abstract: Considering the specialty and requirement of mining production,this paper designed an(interlinkage) gateway between CAN Bus and RS485 Bus with PIC18F248 single-chip microcomputer,and gave the design principle and implementing schemes of software and hardware of the gateway.The gateway was designed to be low-power-consumed,so it is very suitable for coal mine due to its high reliability,simple structure,low cost and good real-time quality.