Abstract: With the development of the intelligent mine, open-pit coal mine unmanned transportation system has gradually carried out experimental applications. But the application of new technologies brings new management challenges. The existing emergency management system can not meet the needs of the new status. In order to solve the above problems, the emergency management system of the unmanned transportation system in the open-pit coal mine is studied from four aspects: the analysis of the present situation, the design of the system framework, the system construction and the future development trend. Firstly, the status quo of emergency management of unmanned transportation system in the open-pit coal mine is analyzed. The new challenges that may be faced in emergency management are summarized. The challenges include the lack of experience in the application of new technologies, the lack of targeted emergency management content, and the lack of clarity in the event disposal process and content caused by the weak capability of information sharing and coordination. Secondly, the emergency of the unmanned transportation system in the open pit coal mine is classified (including transportation accident, meteorological disaster, communication accident, fire and others). According to the general requirements of safety and emergency management of open pit coal mine enterprises, the framework of the emergency management system of the unmanned transportation system in the open pit is designed. The framework covers the whole links of prevention, monitoring, disposal and recovery of the sudden crisis in the production process. Thirdly, the construction of the emergency management system of the unmanned transportation system in the open pit coal mine is analyzed in detail from four aspects of emergency preparation and drill, monitoring and early warning, emergency response and disposal management. Finally, based on the development background of intelligent mine, the future development trend of emergency management system in the open-pit coal mine is discussed, including the integration of dispatching management and emergency disposal, the intellectualization of emergency plan preparation, and the emphasis on information security. The research results provide a reference for further improving the emergency management theory of unmanned transportation system in open-pit coal mine and formulating effective emergency plan.