Abstract: Fire area isolation is the main method to effectively control the development and spread of fire, which can cut off the reaction chain of secondary accidents and reduce the scope of fire impact. In order to solve the problem that the commonly used fire airtight isolation measures cannot provide real-time dynamic monitoring and forecasting of the airtight environment, a dynamic information perception and emergency isolation system for mine fire environment is designed. The monitoring nodes are arranged in the predetermined dangerous areas, and the environmental information of multiple measuring points are collected and transmitted to the ground monitoring platform through multi-parameter sensors and infrared cameras. When abnormal data is detected, the system alarms and controls the airtight isolation device to open through remote control to realize the airtight bag filling. The bag is expanded from the storage bin to the entire section through the preset slide rail drive system to realize emergency airtight isolation. Real-time monitoring of the internal air pressure of the bag is carried out through high-precision pressure sensors. When the internal pressure of the bag is lower than the lower limit of the safety range, the automatic air-filling device of the bag is activated to replenish the air volume of the bag. When the internal pressure reaches the upper limit of the set range, the device automatically stop inflation to enhance the airtight effect. Field test results show that the system achieves the functions of real-time collection and alarm of fire environment parameters, remote control of airtight isolation device, etc. The airtight bag can be opened within 5 min, and the pressure inside the airtight bag remains basically stable after stopping inflation, which meets the requirements of field applications.