Abstract: In order to solve the problems of low real-time, insufficient coverage and low reusability of the coal mine safety control system with hidden danger management as the core, the construction of a comprehensive prevention and control system of coal mine safety based on risk management and control is proposed. The overall management and control of coal mine risks is carried out through risk identification and implementation of risk control measures, dynamic risk monitoring and closed-loop management of hidden dangers. Based on the results of major disaster risk identification, the system integrates traditional single safety monitoring systems and intelligent ventilation, drainage and power supply systems to achieve comprehensive monitoring, data analysis, early warning and abnormal linkage treatment of major disaster risks. Taking the coal mine enterprise risk database as the core, the system forms and fits safety risk index according to the effects of different levels of safety risk control so as to realize the evaluation and the early warning of abnormalities of comprehensive prevention and control system of coal mine safety. The comprehensive prevention and control system of coal mine safety based on risk management and control helps to realize the pre-control of risks in personnel operation behavior, equipment safety status, environmental safety situation and management safety so as to achieve the goal of preventing and controlling major risks and containing major accidents.