The paper introduced design of a data collection system of simulation training for using self-rescuer based on radio frequency technology and introduced design of its software and hardware in details.The system can collect physiological data such as heart rate,body temperature and so on of underground operating workers when accidents in coal mine underground are simulated in laboratory environment,and can train underground operating workers with pertinency according to the data.The experiment result showed that the system has easy operation and stable performance,and it can get physiological data of trained person efficiently and correctly,which fills the gap of field of existing simulation training for using self-rescuer.