Abstract: Combining digital twin with artificial intelligence (AI) technology, a new idea for smart mine construction based on digital twin + AI was proposed. Development path of smart mine technology was explored, and characteristics, application fields and development trends of digital twin technology were studied, and it was pointed out that digital twin is an inevitable trend of digital mine development. The theoretical framework of smart mine based on digital twin + AI was proposed, and mine digital twin model was constructed which includes mine full element physical entity, mine information physics fusion layer, mine digital twin model, mine twin data interaction layer, mine application intelligent service layer from bottom to top. Ubiquitous perception, collaborative control and intelligent decision-making and optimization of the intelligent mine can be realized based on the model. Starting from actual application requirements, key technologies such as smart mine model construction technology, smart mining digital twin technology, mine intelligent control technology, mine equipment fault prediction, and human-computer interaction based on digital twin were discussed. By studying the application of digital twin in smart mine, it provides ideas for the application of AI technology in smart mine and theoretical reference for the construction of new engineering discipline in smart mine in the future.