Abstract: In order to solve problems of high cost, single function and lack of on-line parameter adjustment of existing monitoring instruments for mine geological safety, the paper proposed a realization method of virtual instrument system for microseismic monitoring, and mainly introduced design schemes of data acquisition card based on ARM and monitoring software of upper computer based on LabVIEW. The system has realized functions of on-line parameter setting and real-time acquisition, filtering, storage, analysis, wave display and printing of microseismic monitoring data of multi-channel.